Daily Archives: 3 مهر 1402

Hematopoietic stem cell transplant failure (GVHD)

Hematopoietic stem cell transplant failure (GVHD)

Allogeneic hematopoietic cell transplantation (allo-HCT) is a curative therapy for hematologic disorders, but its success is complicated by graft-versus-host disease (GvHD). Since allo-HSCT requires conditioning, tissue damaging events will occur in all patients undergoing this procedure. Chemotherapy and radiotherapy used during the conditioning regimens induce tissue damage and consequently release exogenous and endogenous molecules that […]