PML-RAR is a unique subtype of acute myeloid leukemia (AML) called acute promyelocytic leukemia (APL). In this disease, promyelocytic cells (immature white blood cells) are overproduced and accumulate in the bone marrow. APL is caused by a genetic fusion between two genes, PML and RAR, forming a fusion gene called PML-RAR. Translocation (chromosomal displacement) between […]
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BCR-ABL test is a genetic test used to diagnose certain blood cancers. In this test, the presence of the BCR-ABL gene sequence on chromosome 22 is examined, which helps diagnose this type of cancer. Additionally, this test is used to monitor treatment effectiveness and diagnose cancer recurrence. BCR-ABL is actually an abnormal gene sequence that […]

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